Whakamatau Alpha-Fetoprotein (AFP)

Toka Te Manawa

• He aha te whakamatautau alpha-fetoprotein (AFP)?
• Hei aha te whakamahi?
• He aha i hiahiatia ai e ahau he whakamatautau AFP?
• Ka ahatia i te wa o te whakamatautauranga a te AFP?
• Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
• He raru pea mo te whakamatautau?
• He aha te tikanga o nga hua?
• He mea ano me mohio au mo te whakamatautau a te AFP?
• Tohutoro

He aha te whakamatautau alpha-fetoprotein (AFP)?

Ko te Alpha-fetoprotein (AFP) he pūmua i hangaia i te ate o te kukune e whanake ana. I te whanaketanga o te peepi, ka haere etahi o nga AFP ki roto i te waahi ka uru ki te toto o te whaea. Ko te whakamatautau a te AFP te tohu i te taumata o te AFP i roto i nga wa hapu i te wa o te huringa tuarua o te haputanga. He nui, he iti rawa ranei te AFP i roto i te toto o te whaea, he tohu pea no te koha o te whanautanga, o tetahi atu ahuatanga ranei. Kei roto i enei:

• Ko te koha o te ngongo neural, he mate kino ka whanakehia te roro o te peepi me te tuaiwi ranei
• Down Syndrome, he mate whakapapa e whakararu ana i te hinengaro hinengaro me te roa o te whanaketanga
• He mahanga he maha ranei nga whanautanga, na te mea neke atu i te kotahi te peepi e whanau ana i te AFP
• Te whakatau he i te waa tika, na te mea ka rereke nga taumata AFP i te wa e hapu ana

Ko etahi ingoa: AFP Maternal; Serum Serum AFP; MSAFP mata

Hei aha te whakamahi?

Ka whakamahia he whakamatautau toto a te AFP ki te tirotiro i te kohanga e whanake haere ana mo te raru o te whanautanga me nga mate whakapapa, penei i te koha o te ngongo neural Down Down ranei.

He aha i hiahiatia ai e ahau he whakamatautau AFP?

E kii ana te American Pregnancy Association me tuku nga whakamatautau ki nga waahine katoa i etahi wa i waenga i te 15 ki te 20 wiki o te haputanga. Ka tino taunakihia te whakamatautau mena ka:

• Me whai whanau whanau nga koha whanau
• He 35 tau neke atu ranei
• Kia mate huka

Ka ahatia i te wa o te whakamatautauranga a te AFP?

Ka tangohia e tetahi tohunga ngaio hauora tetahi tauira toto mai i te uaua i roto i to ringa, ma te whakamahi i te ngira iti. Whai muri i te kuhunga o te ngira, ka kohia he toto iti ki roto i te ipuipu, ipu ranei. Akene he iti to ngau ka puta te ngira ki waho ka puta atu ranei. Ko te tikanga ka iti ake i te rima meneti tenei.

Me mahi e au tetahi mea hei whakareri mo te whakamatautau?

Kaore e hiahiatia he whakaritenga motuhake mo te whakamatautau a te AFP.

He raru pea mo te whakamatautau?

He iti noa te tuponotanga ki a koe, ki to peepi ranei me te whakamatautau toto a te AFP. Ka mamae pea koe, ka maru ranei koe i te waahi i maka ai te ngira, engari ko te nuinga o nga tohu ka tere wawe. Ko tetahi atu whakamatautau i kiia ko te amniocentesis he tohu tika ake mo te Down syndrome me etahi atu kohakore whanau, engari he iti noa te tuponotanga o te whakamatau kia mate ai te haputanga.

He aha te tikanga o nga hua?

Mena he tiketike ake o hua i runga ake i nga taumata noa o te AFP, ko te tikanga he mate pukupuku ngongo to peepi penei i te spina bifida, he ahuatanga kaore e piri nga wheua o te tuaiwi i te taha o te tuaiwi, te anencephaly ranei, he ahuatanga e kaore te roro e whanake tika.

Mena he iti ake te kitenga o au kitenga i nga taumata o te AFP, ko te tikanga he mate whakapapa to peepi penei i te Down Syndrome, he ahuatanga e raru ai te hinengaro me te whanaketanga.

Mena kaore i te rite nga taumata o te AFP, ehara i te mea he raru kei to peepi. Ko te tikanga kei te nui ake i te kotahi to peepi kua hapa to waa kua tae mai ranei. Akene ka whiwhi koe i te hua-hape-pai. Ko te tikanga ko o hua ka puta he raru, engari kei te hauora to peepi. Mena ka whakaatu he teitei ake, he iti ake ranei i te taumata maamaa o te AFP, tera pea ka nui ake nga whakamatautau ka taea e koe hei whakatau mate.

Ako atu mo nga whakamatautau taiwhanga, awhe tohutoro, me te maarama ki nga hua.

He mea ano me mohio au mo te whakamatautau a te AFP?

Ko nga whakamatautau a te AFP he maha nga waahanga o te whakamatautau whanau i mua i te wa e kiia ana he maha nga tohu tohu toru ranei. Hei taapiri atu ki te AFP, he whakamatau takitoru te whakamaatautau i te hCG, he homoni e mahia ana e te kopu, me te estriol, he momo estrogen na te kopu i hanga. Ka taea e enei whakamatautau te awhina i te mate Down syndrome me etahi atu mate ira.

Mena he nui ake to tuponotanga ki a koe mo to peepi me nga ngoikoretanga o te whanautanga, ka taunaki pea to kaiwhakarato i tetahi whakamatautau hou e kiia ana ko te DNA-kore-ira (CFDNA) He whakamatautau toto tenei ka taea te hoatu i nga wa katoa o te 10^th wiki o te hapu. Ka taea te whakaatu mena ka whakaatu mena he tupono pea te peepi o to peepi ki te pangia e te mate Down Down me etahi atu mate ira ranei.

Tohutoro

1. American Pregnancy Association [Ipurangi]. Irving (TX): American Pregnancy Association; c2017. Tirohanga Aroha-Fetoprotein Serum Maternal (MSAFP) [whakahoutia 2016 Sep 2; whakahuahia 2017 Jun 5]; [tata ki te 3 nga mata]. Wātea mai i: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
2. American Pregnancy Association [Ipurangi]. Irving (TX): American Pregnancy Association; c2017. Whakamatau Tiwhikete Tolu [whakahoutia 2016 Sep 2; whakahuahia 2017 Jun 5]; [tata ki te 3 nga mata]. Wātea mai i: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
3. Graves JC, Miller KE, Kaihoko AD. Te Whakatakotoranga Tauhuri Takitoru Tuatoru Wahine i te Maehe. Am Tohunga Takuta [Ipurangi]. 2002 Maehe 1 [cited 2017 Jun 5]; 65 (5): 915–921. Wātea mai i: https://www.aafp.org/afp/2002/0301/p915.html
4. Johns Hopkins Medicine [Ipurangi]. Johns Hopkins Rongoa; Whare Pukapuka Hauora: Nga Whakamatau Maamaa i Te wa e hapu ana [te tau 2017 Jun 5]; [tata ki te 3 nga mata]. Wātea mai i: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
5. Nga Whakamatautau Reipa Aipurangi [Ipurangi]. Washington D.C .: American Association mo te Haumanu Haumanu; c2001–2019. Te Tirohanga Serum Whaanau, Te Tuarua Tuatoru; [whakahoutia 2019 Mei 6; whakahuahia 2019 Jun 4]; [tata ki te 2 nga mata]. Wātea mai i: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
6. Nga Whakamatautau Reipa Aipurangi [Ipurangi]. American Association mo te Haumanu Haumanu; c2001–2017. Papakupu: Spina Bifida [whakahua i te 2017 Jun 5]; [tata ki te 3 nga mata]. Wātea mai i: https://labtestsonline.org/glossary/spina-bifida
7. Merck Manual Kaihoko Putanga [Ipurangi]. Kenilworth (NJ): Merck & Co. Inc.; c2017. Tuhinga o mua Prenatal Diagnostic Testing [whakahoutia 2017 Jun; whakahuahia 2019 Pipiri 4]; [tata ki te 3 nga mata]. Wātea mai i: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorder/prenatal-diagnostic-testing
8. National Center for Advancing Translational Science / Genetic and Rare Diseases Center [Ipurangi]. Gaithersburg (MD): U.S. Tari Hauora me te Ratonga Tangata; Nga Korero Ngongo Neural [whakahoutia 2013 Nov 6; whakahuahia 2017 Jun 5]; [tata ki te 3 nga mata]. Wātea mai i: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
9. National Heart, Lung, and Blood Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. He aha nga morearea o nga whakamatautau toto? [whakahoutia 2012 Hanuere 6; whakahuahia 2017 Jun 5]; [tata ki te 5 o nga mata]. Wātea mai i: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
10. National Heart, Lung, and Blood Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. He Aha Me Tono Ki Nga Toto Toto [whakahoutia 2012 Hanu 6; whakahuahia 2017 Jun 5]; [e 4 pea nga mata]. Wātea mai i: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. Whare Wananga o Rochester Medical Center [Ipurangi]. Rochester (NY): Whare Wananga o Rochester Medical Center; c2017. Encyclopedia Hauora: Alpha-fetoprotein (AFP) [whakahua i te 2017 Jun 5]; [tata ki te 2 nga mata]. Wātea mai i: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
12. Whare Wananga o Rochester Medical Center [Ipurangi]. Rochester (NY): Whare Wananga o Rochester Medical Center; c2017. Encyclopedia Hauora: Alpha-fetoprotein (Toto) [kiia 2017 Jun 5]; [tata ki te 2 nga mata]. Wātea mai i: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
13. Hauora UW [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2017. Korero Hauora: Alpha-Fetoprotein (AFP) i te Toto [whakahoutia 2016 Jun 30; whakahuahia 2017 Jun 5]; [tata ki te 5 o nga mata]. Wātea mai i: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
14. Hauora UW [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2017. Korero Hauora: Takitoru Tuatoru Tuatoru ranei mo nga Raru Whanau [whakahoutia 2016 Jun 30; whakahuahia 2017 Jun 5]; [tata ki te 5 o nga mata]. Wātea mai i: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec

Ko nga korero kei tenei papaanga kaua e whakamahia hei whakakapi mo te tiaki ngaio ngaio, tohutohu ranei. Whakapa atu ki te kaiwhakarato hauora mena he paatai ​​taau mo to hauora.