Tauwehenga XII (Hageman factor) ngoikoretanga

Ko te ngoikoretanga o te Take XII he mate tuku iho e pa ana ki te pūmua (tauwehe XII) e uru ana ki te whakaheke toto.

Ka toto ana koe, ka puta etahi urupare ki te tinana ka awhina i te whakaheke toto. Ko tenei mahinga e kiia ana ko te cascade coagulation. Kei roto he porotini motuhake e kiia ana ko te koohuru, ko te take o te whakakotahitanga ranei. Ka nui ake pea to tuponotanga o te toto mena ka ngaro tetahi, neke atu ranei o enei ahuatanga, kaore ranei e mahi kia rite ki nga wa o mua.

Ko te Take XII tetahi mea. Ko te kore o tenei take kaore koe e mate i te toto totika. Engari, he roa te toto i te waa noa ki te ngongo ki te ipuipu.

Ko te ngoikoretanga o te Take XII he mate onge tuku iho.

Te tikanga kaore he tohu.

I te nuinga o te wa ka kitea te ngoikoretanga o te Take XII i te wa e oti ana nga whakamatautau ruumaru mo te tirotiro i ia ra

Kei roto i nga whakamatautau:

• Tauwehenga XII whakamatautau ki te ine i te ngohe o te tauwehe XII
• Te waahanga thromboplastin wahanga (PTT) hei tirotiro he pehea te roa o te whakaheke toto
• Ko te rangahau whakaranu, he whakamatautau PTT motuhake hei whakau i te koretake o te take XII

Te tikanga kaore e hiahiatia te maimoatanga.

Ma enei rauemi e whakarato etahi atu korero mo te ngoikoretanga o te tauwehenga XII:

• National Hemophilia Foundation - www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies/Factor-XII
• National Organisation for Rare Disorder - rarediseases.org/rare-diseases/factor-xii-deficiency
• NIH Genetic and Rare Diseases Information Center - rarediseases.info.nih.gov/diseases/6558/factor-xii-deficiency

Ko te mutunga ka pai kia kore he maimoatanga.

Te tikanga kaore he raru.

I te nuinga o te wa ka kitea e te kaiwhakarato hauora tenei ahuatanga ka rere ana i etahi atu whakamatautau taiwhanga.

He mate tuku iho tenei. Kaore he huarahi e mohiotia ana hei aukati.

F12 ngoikoretanga; Hageman tauwehenga ngoikoretanga; Hageman huru; HAF hapanga

• Pakihi toto

Gailani D, Wheeler AP, Neff AT. Nga ngoikoretanga o te tauwehenga onge. I roto i: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Maatauranga Maatauranga me te Mahi. Ed 7. Philadelphia, PA: Elsevier; 2018: chap 137.

Hall JE. Hemostasis me te toto toto. I roto i: Hall JE, ed. Guyton me te Pukapuka Pukapuka a Hall mo te Hauora Hauora. 13th ed. Philadelphia, PA: Elsevier; 2016: chap 37.

Ragni MV. Nga mate hemorrhagic: nga ngoikoretanga o te waahanga I roto i: Goldman L, Schafer AI, eds. Te rongoa Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 174.