HER2 (Mate Mate pukupuku) Whakamatau

Toka Te Manawa

• He aha te whakamatautau i te mate pukupuku uma o HER2?
• Hei aha te whakamahi?
• He aha i hiahia ai ahau ki te whakamatautauranga mate pukupuku uma HER2?
• He aha te mahi i te wa o te whakamatautauranga mate pukupuku uma HER2?
• Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
• He raru pea mo te whakamatautau?
• He aha te tikanga o nga hua?
• He mea ano me mohio au mo te whakamatautauranga mate pukupuku uma o HER2?
• Tohutoro

He aha te whakamatautau i te mate pukupuku uma o HER2?

Ko te HER2 e tohu ana mo te kaiwhakawhiwhi take tipua tangata 2. He ira e hanga ana i te pūmua ki te mata o nga pukupuku uma. Ka uru atu ki te tipu tipu noa o te pūtau.

Ko te ira te waahanga taketake o te whakapapa, i heke mai i to whaea me to papa. I etahi mate pukupuku, ina koa ko te mate pukupuku o te u, ka huri te HER2 ira (ka whakarereke) ka taapiri i nga waahanga o te ira. Ka pa ana tenei, ka nui rawa te porotaka a te HER2 HER2, na te mea ka wehewehe te wehenga, ka tere hoki te tipu.

Ko nga mate pukupuku me te nui o te hinu o te HER2 e mohiotia ana ko te HER2-pai. Ko nga mate pukupuku e iti ana te taumata o te poroteini e mohiotia ana ko HER2-kino. Tata ki te 20 ōrau o nga mate pukupuku uma he HER2-pai.

Ko te whakamatautau HER2 ka tirohia te tauira o te kiko puku. Ko nga huarahi noa hei whakamatautau i te kiko puku ko te:

• Ko te whakamatautau Immunohistochemistry (IHC) te mehua i te pūmua HER2 kei runga i te mata o nga pūtau
• Ko te whakamatautau fluorescence in situ hybridization (FISH) e rapu ana mo etahi atu taarua o te ira HER2

Ko nga momo whakamatautau e rua ka tohu mena he mate pukupuku HER2-pai koe. Ko nga maimoatanga e aro nui ana ki te mate pukupuku uma o te mate pukupuku-tino pai rawa atu.

Ko etahi ingoa: ko te kaiwhakawhiwhi whakatipuranga tangata 2 kaiwhiwhi, ERBB2 whakarahi, HER2 whakaputanga kaha, HER2 / neu whakamātautau

Hei aha te whakamahi?

Ko te whakamatautau HER2 te nuinga e whakamahia ana kia kitea mena he pai te HER2 mo te mate pukupuku ranei. I etahi wa ka whakamahia ano kia kite mena kei te urupare te mate pukupuku ki te maimoatanga mena kua hoki mai ranei te mate pukupuku i muri o te maimoatanga.

He aha i hiahia ai ahau ki te whakamatautauranga mate pukupuku uma HER2?

Mena kua tohua koe ki te mate pukupuku o te u, ka hiahia pea koe ki tenei whakamatautau kia mohio koe mena he pai te mate pukupuku o te HER2 he HER2 ranei. Mena kei te rongohia koe mo te mate pukupuku uma o te mate HER2-pai, akene me whakamatautauria koe ki:

• Tirohia mena kei te pai to maimoatanga. Ko nga taumata noa o te HER2 te tikanga kei te whakautu koe ki nga maimoatanga. Ko nga taumata tiketike tera pea kaore te maimoatanga e mahi.
• Tirohia mena kua hoki mai te mate pukupuku i muri o te maimoatanga.

He aha te mahi i te wa o te whakamatautauranga mate pukupuku uma HER2?

Ko te nuinga o nga whakamātautau HER2, ko te tango tauira o te kiko puku i roto i te tikanga e kiia ana ko te koiora. E toru nga momo tikanga koiora matua:

• Te koiora koiora koiora koiora, e whakamahi ana i te ngira tino angiangi hei tango i tetahi tauira o nga pukupuku uma, te waipiro ranei
• Biopsy ngira matua, e whakamahi ana i te ngira rahi ake hei tango tauira
• Haurongo taatai, e tango ana i tetahi tauira i roto i te tikanga iti, i te tūroro tūroro

Ko te wawata ngira pai me te koiora koi ngira matua te tikanga ko nga mahi e whai ake nei:

• Ka takoto koe ki to taha ka noho ranei i runga i te teepu whakamātautau.
• Ma te kaiwhakarato hauora e horoi i te papaa koiora ka werohia ki te rongoa rongoa kia kore ai koe e mamae i te wa o te mahinga.
• Ka pore noa te rohe, ka whakauruhia e te kaiwhakarato he ngira wawata pai te ngira koiora koiora ranei ki te waahi koiora ka tango i tetahi tauira kiko, waikore ranei.
• Akene he iti ake te pehanga i a koe ka tangohia ana te tauira.
• Ka tukuna te peehi ki te waahi koiora kia mutu ra ano te toto.
• Ka tohaina e to kaiwhakarato he takai taatai ​​i te waahi koiora.

I roto i te waahanga koiora, ka tapahia e tetahi taote tipua he kiri iti ki to kiri kia tangohia katoa, tetahi waahanga ranei o te puoro u. I etahi wa ka mahia he koiora pokanga mena kaare e tae te puranga ki te koiora ngira. Ko nga tikanga biopsies taatai ​​e whai ake nei.

• Ka takoto koe i runga i te teepu whakahaere. He IV (raina haurangi) ka tuu pea ki to ringa, ki to ringa ranei.
• Ka whakawhiwhia pea ki a koe te rongoa, e kiia ana he kaiwhakamarie, kia pai ai to noho.
• Ka whakawhiwhia koe ki te rongoa kaainga a rohe, whanui ranei kia kore ai koe e mamae i te waa o te mahinga.
  • Mo te mate rongoa o te rohe, ka werohia e te kaiwhakarato ratonga hauora te papa koiora ki te rongoa mo te rohe.
  • Mo te mate rongoa whaanui, ma te tohunga i huaina ko te tohunga rongoa rongoa ka hoatu he rongoa ki a koe kia kore ai koe e mohio i nga wa o te mahinga.
• Ka koretake te waahanga koiora, kaore koe i te mohio ranei, ka tapahia e te taote taatai ​​te tapahanga iti ki roto i te u, ka tangohia tetahi waahanga, tetahi waahanga ranei. Ka tangohia pea etahi kiko huri noa i te puranga.
• Ko te motu i roto i to kiri ka katihia ki te tuitui, ki te takai piripiri ranei.

Ko te momo koiora kei a koe ka whakawhirinaki ki nga ahuatanga rereke, tae atu ki te rahi me te waahi o te puku. Ka taea hoki te mehua HER2 i roto i te whakamatautau toto, engari ko te whakamatautau toto mo te HER2 kaore ano kia kitea he pai mo te nuinga o nga tuuroro. Na kaore i te nuinga o te waa e taunaki ana.

Whai muri i te tangohanga o to tauira kiko, ka whakamatauria i tetahi o nga ara e rua:

• Ka inea te taumata pūmua HER2.
• Ka tirohia te tauira mo etahi kape taapiri o te ira HER2.

Me mahi e au tetahi mea hei whakareri mo te whakamatautau?

Kaore koe e hiahia i etahi whakaritenga motuhake mena kei te whiwhi koe i te rongoa haumanu a te rohe (te whakamoe i te papaa koiora). Mena kei te whiwhi koe i te mate rongoa mate, akene me tere te nohopuku (kaua e kai, inu ranei) mo etahi haora i mua o te pokanga. Ma to taakuta tipua e tohutohu ake. Ano hoki, mena kei te whiwhi koe i te rongoa rongoa rongoa rongoa, mate rongoa whanui ranei, tirohia me whakarite kia taraihia koe e tetahi ki te kaainga. Akene he pukuriri koe ka poraruraru i muri i to ara mai i te mahinga.

He raru pea mo te whakamatautau?

Akene he iti to maru, he toto ranei kei te papa koiora. I etahi wa ka pangia te papaanga. Mena ka peena, ka tukuna koe ki nga antibiotic. Ma te koi biopsy e mate ai etahi atu mamae me te kore e ngakau mamae. Ka taunaki pea to kaiwhakarato hauora ki te whakahau ranei i nga rongoa hei awhina i a koe ki te pai.

He iti noa te tuponotanga ka tirohia o toto. Ka mamae pea koe, ka maru ranei koe i te waahi i maka ai te ngira, engari ko te nuinga o nga tohu ka tere wawe.

He aha te tikanga o nga hua?

Mena he teitei ake te taumata o te pūmua HER2 i te nuinga o te wa, ka kitea ranei he kape taapiri o te ira HER2, akene he mate pukupuku HER2-pai koe. Mena ka whakaatu o hua i te maha o nga pūmua HER2, te ira noa o te HER2 ira, tērā pea ka pāngia koe e te mate pukupuku HER2-kino.

Mena kaore i tino marama, he kino ranei nga hua, ka whakamatautauria pea koe, ma te whakamahi i tetahi tauira tumomo rereke, me te whakamahi ranei i tetahi atu tikanga whakamatautau. I te nuinga o nga wa, ko te IHC (te whakamatautau mo te HER2 protein) ka oti i te tuatahi, ka peia e te ika (whakamatautau mo etahi atu taarua o te ira). He iti rawa te utu o te whakamatautau IHC ana he tere ake te otinga atu i te ika. Engari ko te nuinga o nga tohunga o te u e whakaaro ana he tika ake te whakamatautau IKI.

Ko nga maimoatanga mo te mate pukupuku uma o te mate HER2-tino pai te whakaiti i nga pukupuku pukupuku, me te iti o nga awangawanga. Ko enei maimoatanga kaore e whai kiko ki nga mate pukupuku HER2-kino.

Mena kei te tukuna koe mo te mate pukupuku HER2-pai, ko nga hua noa ka tohu pea koe ki te rongoa. Ko nga hua e whakaatu ana he teitei ake i te moni noa, ka tohu pea kaore i te pai o maimoatanga, kua hoki mai ranei te mate pukupuku i muri o te maimoatanga.

Ako atu mo nga whakamatautau taiwhanga, awhe tohutoro, me te maarama ki nga hua.

He mea ano me mohio au mo te whakamatautauranga mate pukupuku uma o HER2?

Ahakoa te nuinga o te wa e pa ana ki nga waahine, ko te mate pukupuku o te u, tae atu ki te mate pukupuku uma o te mate HER2-pai, ka raru ki nga tane Mena kua tohua tetahi tangata kua pa te mate pukupuku o te u, ka taunaki pea he whakamatautau HER2.

Hei taapiri, ko nga taane me nga waahine ka hiahia kia whakamatautauria te HER2 mena kua kitea he mate pukupuku o te kopu me te kopapa. I etahi wa he nui nga matepukupuku o enei mate pukupuku i te HER2 ka pai pea te aro ki nga maimoatanga mate pukupuku HER2-pai.

Tohutoro

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2. American Cancer Society [Ipurangi]. Atlanta: American Cancer Society Inc. c2018. Mate Mate Mate Mate HER2 [whakahoutia 2017 Sep 25; whakahuahia 2018 Akuhata 11]; [e 4 pea nga mata]. Wātea mai i: https://www.cancer.org/cancer/breast-cancer/understanding-a-breast-cancer-diagnosis/breast-cancer-her2-status.html
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Ko nga korero kei tenei papaanga kaua e whakamahia hei whakakapi mo te tiaki ngaio ngaio, tohutohu ranei. Whakapa atu ki te kaiwhakarato hauora mena he paatai ​​taau mo to hauora.