Kaitito: William Ramirez
Tuhinga O Mua: 24 Hepetema 2021
Rā Whakahou: 13 Noema 2024
Anonim
Human Leukocytic Antigen-B27 (HLA-B27)
Ataata: Human Leukocytic Antigen-B27 (HLA-B27)

Ko te HLA-B27 he whakamatautau toto hei rapu i te pūmua e kitea ana i te mata o nga toto toto ma. Ko te pūmua e kīa nei ko te tangata leukocyte antigen B27 (HLA-B27).

Ko nga antigens leukocyte a te tangata (HLAs) he poroteini hei awhina i te punaha aukati o te tinana ki te whakaatu i te rereketanga i waenga i ona ake ruma me nga mea ke, nga mea kino. I ahu mai i nga tohutohu mai i nga ira tuku iho.

He tauira toto e hiahiatia ana. I te nuinga o te waa, he toto ka ahu mai i te uaua i runga rawa o te tuaono, o muri ranei o te ringa.

I te nuinga o nga wa, kaore he waahanga motuhake hei whakarite mo te whakamatautau.

Ka whakauruhia te ngira ki te utu toto, ka mamae pea koe, he werohanga noa iho ranei te kare e rongo. Muri iho, tera pea ka puta te pupuhi.

Ka whakahau pea to kaiwhakarato hauora tenei whakamatautau kia pai ai te whakatau i te take o te mamae o te hononga, o te pakari, o te pupuhi ranei. Ka taea te whakamatautau me etahi atu whakamatautau, tae atu ki:

  • Pūmua C-urupare
  • Te reiti whakaheke erythrocyte (ESR)
  • Take rheumatoid
  • Hihi-X

Ka whakamahia hoki te whakamatautau HLA ki te taurite i te kiko takoha me te kiko o te tangata e mau ana i te okana okana. Hei tauira, ka taea mena ka hiahiatia e te tangata te tango i te whatukuhu, te whakawhitinga wheua wheua ranei.


Ko te hua noa (kino) ko te tikanga kaore te HLA-B27 e ngaro.

Ko te whakamatautau pai ko te HLA-B27 kei reira. E kii ana he morearea nui-nui atu i te toharite mo te whanake, te raru ranei o te mate autoimmune. Ko te mate autoimmune he ahuatanga ka tupu ka he ana te punaha aukati ki te whakaeke me te whakangaro i nga kiko o te tinana hauora.

Ma te hua pai ka awhina i to kaiwhakarato ki te whakatau mate i tetahi momo mate kaawhiu e kiia nei ko te spondyloarthritis. Ko tenei momo mate kawa ko nga mate e whai ake nei:

  • Spondylitis Ankylosing
  • Nga mate pukupuku e pa ana ki te mate Crohn, ki te mate pukupuku ranei
  • Te mate o te Psoriatic (rumati e pa ana ki te psoriasis)
  • Te rumati urupare
  • Sacroiliitis (mumura o te hononga sacroiliac)
  • Uveitis

Mena he tohu koe, he tohu tohu ranei mo te spondyloarthritis, ma te pai o te whakamatautau HLA-B27 e ahei ai te whakatau i te tohu mate. Heoi, ko te HLA-B27 ka kitea i etahi taangata noa, kaore i te kii he mate koe.

He iti noa nga tuponotanga o te whakaheke toto, engari ka uru pea ki:


  • Te whakaheke toto
  • Te maarere, te ahua marama ranei
  • Hematoma (whakaheke toto i raro o te kiri)
  • Mate (he morearea pea ka pakaru te kiri)

Te leukositiki antigen B27; Ankylosing spondylitis-HLA; Te mate pukupuku Psoriatic-HLA; Uru rumati-HLA

  • Whakamatautau toto

Chernecky CC, Berger BJ. Human Leukocyte Antigen (HLA) B-27 - toto. I roto i: Chernecky CC, Berger BJ, eds. Nga Whakamatau Laboratory me nga Huarahi Taatari. 6 ed. St Louis, MO: Elsevier Saunders; 2013: 654-655.

Fagoaga OR. Antigen leukosit tangata: te matatini whakahoahoa nui o te tangata. I roto i: McPherson RA, Pincus MR, eds. Ko te Tohu Haumanu a Henry me te Whakahaere ma nga Tikanga Laboratory. 23rd ed. St Louis, MO: Elsevier; 2017: chap 49.

Inman RD. Nga spondyloarthropathies. I roto i: Goldman L, Schafer AI, eds. Te rongoa Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 265.


McPherson RA, Massey HD. Tirohanga katoa o te punaha aukati me nga mate aukati. I roto i: McPherson RA, Pincus MR, eds. Ko te Tohu Haumanu a Henry me te Whakahaere ma nga Tikanga Laboratory. 23rd ed. St Louis, MO: Elsevier; 2017: chap 43.

Whakakite JD. Spondyloarthritis. I roto i: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Toronga AJ, Weyand CM, eds. Immunology Haumanu: Nga Tikanga me te Mahi. 5th ed. Philadelphia, PA: Elsevier; 2019: chap 57.

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