Nga Whakamatau Hauora
Toka Te Manawa
- He aha te whakamatautau i te rongoatanga?
- Hei aha te whakamahi?
- He aha i hiahia ai ahau ki te whakamatautau i te rongoatanga?
- He aha te mea e tupu i te wa e whakamatautauria ana te rongoatanga?
- Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
- He raru pea mo te whakamatautau?
- He aha te tikanga o nga hua?
- He mea ano me mohio au mo te whakamatau i te rongoatanga?
- Tohutoro
He aha te whakamatautau i te rongoatanga?
Ko te rongoa rongoa rongoa rongoa rongoa rongoa rongoa rongoa rongoa rongoa rongoa puoro, e kiia ana ko te rongoa rongoa rongoa, ko te ako me pehea te awe o te ira i te uruparenga o te tinana ki etahi rongoa. Ko nga ira nga waahanga o te DNA i tukuna mai i to whaea me to papa. Kei a ratau nga korero e whakatau ana i o ahuatanga motuhake, penei i te teitei me te tae o te karu. Ka raru pea o ira i te ahuru me te whai hua o te rongoa maau.
Ko nga ira pea te take he rite tonu te rongoa i te horopeta kotahi ki nga taangata na roto i nga ahuatanga rereke. Ko nga ira pea te take ka raru etahi taha ki etahi rongoa, ko etahi kaore.
Ko te whakamatautau i te rongo rongoa he titiro ki nga ira motuhake hei awhina i nga momo rongoa me nga rongoa ka tika maau.
Othertahi atu ingoa: pharmacogenomics, whakamātautau pharmacogenomic
Hei aha te whakamahi?
Akene ka taea te whakamahi i te whakamatau Pharmacogenetic ki:
- Tirohia mēnā ka pai pea tetahi rongoa maau
- Rapua he aha te rongoa pai maau
- Matapaetia ka pa he mate kino ki a koe mai i te rongoa
He aha i hiahia ai ahau ki te whakamatautau i te rongoatanga?
Akene ka whakahau to kaiwhakarato hauora i enei whakamatautau i mua i to tiimata i tetahi rongoa, ki te tango ranei koe i te rongoa kaore i te pai, ka peera ranei nga mate kino.
He waatea noa nga whakamatautau rongoa rongoā mo te maha o nga rongoa. Kei raro nei etahi o nga rongoa me nga ira ka taea te whakamatautau. (Ko nga ingoa Gene ka tohaina ki nga reta me nga nama.)
Rongoa | Nga Ira |
---|---|
Warfarin: he whakaheke toto | CYP2C9 me VKORC1 |
Plavix, he whakaheke toto | CYP2C19 |
Nga rongoa antidepressants, rongoa epilepsy | CYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A / C |
Tamoxifen, he rongoa mo te mate pukupuku o te uma | CYPD6 |
Hinengaro Hinengaro | DRD3, CYP2D6, CYP2C19, CYP1A2 |
Nga maimoatanga mo te ngoikoretanga mate aro | D4D4 |
Carbamazepine, he rongoa mo te mate tuuturu | HLA-B * 1502 |
Abacavir, he rongoa mo te HIV | HLA-B * 5701 |
Opioids | OPRM1 |
Statin, nga rongoa hei whakaora i te nui o te cholesterol | SLCO1B1 |
Nga whakamaimoatanga mo te kania o te tamarikitanga me etahi mate koretake | TMPT |
He aha te mea e tupu i te wa e whakamatautauria ana te rongoatanga?
Ko te whakamatautau ka mahia i runga i te toto, i te huware ranei.
Hei whakamatautau toto, ka tangohia e tetahi tohunga ngaio hauora tetahi tauira toto mai i te uaua i roto i to ringa, ma te whakamahi i te ngira iti. Whai muri i te kuhunga o te ngira, ka kohia he toto iti ki roto i te ipuipu, ipu ranei. Akene he iti to ngau ka puta te ngira ki waho ka puta atu ranei. Ko te tikanga ka iti ake i te rima meneti tenei.
Hei whakamatautau i te huware, pātai ki to kaiwhakarato hauora mo nga tohutohu mo te whakarato i to tauira.
Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
Te tikanga kaore e hiahiatia etahi whakaritenga motuhake mo te whakamatautau toto. Mena kei te whakamatautau koe i te huware, kaua e kai, inu, paowa ranei 30 meneti i mua o te whakamatautau.
He raru pea mo te whakamatautau?
He iti noa te tuponotanga ka tirohia o toto. Ka mamae pea koe, ka maru ranei koe i te waahi i maka ai te ngira, engari ko te nuinga o nga tohu ka tere wawe.
Kaore he raru o te whakamatautau tarai.
He aha te tikanga o nga hua?
Mena i whakamatautauria koe i mua i te tiimata i te maimoatanga, ka taea e te whakamatautau te whakaatu mena ka whai hua te rongoa me / ki te tupono ranei koe ki nga awangawanga kino. Ko etahi whakamatautau, penei i etahi mo nga raau rongoa e rongoa ana i te mate tuuturu me te HIV, ka taea te whakaatu mena kei te tupono koe ki nga paanga kino ka mate koe. Mena, ka ngana to kaiwhakarato ki te rapu i tetahi atu maimoatanga.
Ko nga whakamatautau ka puta i mua atu i te wa e rongoa ana koe ka awhina i to kaiwhakaora hauora ki te whakatau i te horopeta tika.
Mena he paatai taau mo o hua, korero ki to kaiwhakarato hauora.
Ako atu mo nga whakamatautau taiwhanga, awhe tohutoro, me te maarama ki nga hua.
He mea ano me mohio au mo te whakamatau i te rongoatanga?
Ka whakamahia noa te whakamatautau Pharmacogenetic kia kitea ai te whakautu a te tangata ki tetahi rongoa motuhake. Ehara i te mea rite ki te whakamatautau ira. Ko te nuinga o nga whakamatautau aa-ira ka whakamahia hei awhina i nga mate ka tupono atu ranei ki te mate, te tohu i te whanaungatanga o te whanau, te tautuhi ranei i tetahi kei te tirotirohanga taihara.
Tohutoro
- Hefti E, Blanco J. Te Whakaaturanga i Te Whakamatau Whakawhitinga Hauora me nga Waehere Whakamaherehere (CPT) o Naianei, He Arotake i nga Mahi o Mua me Naianei. J AHIMA [Ipurangi]. 2016 Hanu [i tohuhia i te 2018 Jun 1]; 87 (1): 56–9. Wātea mai i: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
- Nga Whakamatautau Reipa Aipurangi [Ipurangi]. Washington D.C: American Association mo te Haumanu Haumanu; c2001–2018. Nga Whakamatau Haumaru; [whakahoutia 2018 Jun 1; whakahuahia 2018 Jun 1]; [tata ki te 2 nga mata]. Wātea mai i: https://labtestsonline.org/tests/pharmacogenetic-tests
- Nga Whakamatautau Reipa Aipurangi [Ipurangi]. Washington D.C: American Association mo te Haumanu Haumanu; c2001–2018. Te Ao o te Whakamatau Whakamatau; [whakahoutia 2017 Nov 6; whakahuahia 2018 Jun 1]; [tata ki te 2 nga mata]. Wātea mai i: https://labtestsonline.org/articles/genetic-testing?start=4
- Mayo Clinic: Pokapū mo te Takitahi Takitahi [Ipurangi]. Mayo Foundation mo te Whakaakoranga Hauora me te Rangahau; c1998–2018. Whakamatau-Whakamatau-Ira; [cited 2018 Jun 1]; [tata ki te 3 nga mata]. Wātea mai i: http://mayoresearch.mayo.edu/center-for-individualised-medicine/drug-gene-testing.asp
- Mayo Clinic: Pokapū mo te Takitahi Takitahi [Ipurangi]. Mayo Foundation mo te Whakaakoranga Hauora me te Rangahau; c1998–2018. CYP2D6 / Tamoxifen Whakamatau Labacacogenomic Lab; [cited 2018 Jun 1]; [tata ki te 5 o nga mata].Wātea mai i: http://mayoresearch.mayo.edu/center-for-individualized-medisin/cyp2d6-tamoxifen.asp
- Mayo Clinic: Pokapū mo te Takitahi Takitahi [Ipurangi]. Mayo Foundation mo te Whakaakoranga Hauora me te Rangahau; c1998–2018. HLA-B * 1502 / Carbamazepine Pharmacogenomic Lab Whakamatau; [cited 2018 Jun 1]; [e 4 pea nga mata]. Wātea mai i: http://mayoresearch.mayo.edu/center-for-individualised-medicine/hlab1502-carbamazephine.asp
- Mayo Clinic: Pokapū mo te Takitahi Takitahi [Ipurangi]. Mayo Foundation mo te Whakaakoranga Hauora me te Rangahau; c1998–2018. HLA-B * 5701 / Whakamatau Labacacogenomic Lab; [cited 2018 Jun 1]; [e 4 pea nga mata]. Wātea mai i: http://mayoresearch.mayo.edu/center-for-individualised-medicine/hlab5701-abacavir.asp
- Mayo Clinic: Mayo Medical Laboratories [Ipurangi]. Mayo Foundation mo te Whakaakoranga Hauora me te Rangahau; c1995–2018. ID Whakamatautau: PGXFP: Paewhiri Farmacogenomics Arotahi: Tauira; [cited 2018 Jun 1]; [tata ki te 3 nga mata]. Wātea mai i: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
- National Cancer Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. NCI Papakupu mo nga Tikanga Mate Mate: ira; [cited 2018 Jun 1]; [tata ki te 3 nga mata]. Wātea mai i: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
- National Heart, Lung, and Blood Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. Nga Whakamatau Toto; [cited 2018 Jun 1]; [tata ki te 3 nga mata]. Wātea mai i: https://www.nhlbi.nih.gov/health-topics/blood-tests
- NIH National Institute of General Medical Science [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. Pharmacogenomics; [whakahoutia 2017 Oketopa; whakahuahia 2018 Jun 1]; [e 4 pea nga mata]. Wātea mai i: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
- NIH U.S. National Library of Medicine: Genetics Home Tohunga [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. He aha te mea ko te pharmacogenomics ?; 2018 Mei 29 [i whakahuahia i te 2018 Jun 1]; [e 4 pea nga mata]. Wātea mai i: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
- Hauora UF: Te Whare Waananga o Florida Hauora [Ipurangi]. Whare Waananga o Florida; c2018. Te awe o to ira i nga rongoa e tika ana maau; 2016 Jan 11 [whakahoutia 2018 Jun 1; whakahuahia 2018 Jun 1]; [tata ki te 2 nga mata]. Wātea mai i: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are- Right-you
- UW Hauora American Family Children's Hospital [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2018. Hauora Tamariki: Pharmacogenomics; [cited 2018 Jun 1]; [e 4 pea nga mata]. Wātea mai i: https://www.uwhealthkids.org/kidshealth/en/father/pharmacogenomics.html/
Ko nga korero kei tenei papaanga kaua e whakamahia hei whakakapi mo te tiaki ngaio ngaio, tohutohu ranei. Whakapa atu ki te kaiwhakarato hauora mena he paatai taau mo to hauora.