Tohu-1 Antitrypsin Whakamatau
Toka Te Manawa
- He aha te whakamatautau alpha-1 antitrypsin (AAT)?
- Hei aha te whakamahi?
- He aha i hiahiatia ai e ahau he whakamatautau AAT?
- Ka ahatia i te wa o te whakamatautau AAT?
- Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
- He raru pea mo te whakamatautau?
- He aha te tikanga o nga hua?
- He mea ano me mohio au mo te whakamatautau AAT?
- Tohutoro
He aha te whakamatautau alpha-1 antitrypsin (AAT)?
Ko tenei whakamatautau ka whanganga i te nui o te alpha-1 antitrypsin (AAT) kei roto i te toto. Ko te AAT he pūmua i hangaia i te ate. Ka awhina i a koe ki te tiaki i o puhukahu mai i nga kino me nga mate, penei i te emehimia me te mate aukati tonu (COPD).
Ko te AAT e hangaia ana e etahi ira i roto i to tinana. Ko te ira te waeine taketake o te whakapapa i heke i o maatua. Kei a ratau nga korero e whakatau ana i o ahuatanga motuhake, penei i te teitei me te tae o te karu. Ka riro i te katoa e rua nga kape o te ira ka hanga AAT, kotahi mai i to ratau papa me tetahi mai i to ratau whaea. Mena he rereketanga (huringa) kei roto i tetahi, i nga kape e rua ranei o tenei ira, ka iti ake te AAT, te AAT ranei o to tinana e kore e pai te mahi.
- Mena e rua nga kape o te ira ka whakarereke, te tikanga kei a koe te mate e kiia nei ko te ngoikoretanga AAT. Ko nga taangata e whai ana i tenei raru he nui ake te morearea kia pangia e te mate pukupuku, te kino ranei o te ate i mua i te 45 tau.
- Mena he kotahi te ira AAT kua hurihia e koe, ka iti ake pea i a koe te nuinga o te AAT, engari he ngawari, kaore ranei he tohu o te mate. Ko nga taangata e kotahi ana te ira whakarake he kaitautoko mo te ngoikoretanga AAT. Ko te tikanga kaore o mate i a koe, engari ka taea e koe te tuku i te ira kua whakarakei ki o tamariki.
Ma te whakamatautau AAT e whakaatu mena kei te whakarereke koe i te ira e tuu ana koe i te mate.
Ko etahi atu ingoa: A1AT, AAT, alpha-1-antiprotease deficience, α1-antitrypsin
Hei aha te whakamahi?
I te nuinga o te wa ka whakamahia te whakamatautau AAT hei awhina i te mate AAT i nga taangata e pa ana ki te mate pukupuku i te wa iti (45 nga tau neke atu ranei) kaore o ratau take morearea penei i te momi hikareti.
Ka taea hoki te whakamahi i te whakamatautau kia kitea he momo mate ate kaore i kitea i roto i nga kohungahunga.
He aha i hiahiatia ai e ahau he whakamatautau AAT?
Ka hiahia pea koe ki te whakamatautau AAT mena kei raro koe i te 45 tau, ehara koe i te kaipaipa, e tohu ana koe i nga mate pukupuku, tae atu ki:
- Wheezing
- Te manawa poto
- Mare maroke
- Tere atu i te paatoi o te ngakau i to wa e tu ana
- Nga raru tirohanga
- Asthma e kore e aro pai ki te maimoatanga
Ka puta pea i a koe tenei whakamatautau mena he hitori o te whanau he ngoikore ki te AAT.
Ko te ngoikore o te AAT i roto i nga peepi e pa ana ki te ate. No reira ka hiahia pea to peepi ki te whakamatautau AAT mena ka kitea e tana kaiwhakaora hauora nga tohu o te mate ate. Kei roto i enei:
- Jaundice, he kowhai o te kiri me nga karu e neke atu ana i te wiki e rua ranei
- He korara kua whakanuia
- Ngatata pinepine
Ka ahatia i te wa o te whakamatautau AAT?
Ka tangohia e tetahi tohunga ngaio hauora tetahi tauira toto mai i te uaua i roto i to ringa, ma te whakamahi i te ngira iti. Whai muri i te kuhunga o te ngira, ka kohia he toto iti ki roto i te ipuipu, ipu ranei. Akene he iti to ngau ka puta te ngira ki waho ka puta atu ranei. Ko te tikanga ka iti ake i te rima meneti tenei.
Me mahi e au tetahi mea hei whakareri mo te whakamatautau?
Kaore koe e hiahia i etahi whakaritenga motuhake mo te whakamatautau AAT.
He raru pea mo te whakamatautau?
He iti noa te tuponotanga o te tinana ki te whakamatautau toto. Ka mamae pea koe, ka maru ranei koe i te waahi i maka ai te ngira, engari ko te nuinga o nga tohu ka tere wawe.
He aha te tikanga o nga hua?
Mena he iti ake i te nuinga o te AAT te whakaatu i o kitenga, akene he kotahi, e rua ranei nga ira AAT kua hurihia e koe. Ki te heke te taumata, tera pea ka rua nga momo ira e mutate me te ngoikore o te AAT.
Mena kua tohua koe he ngoikore ki te AAT, ka taea e koe te whai huarahi ki te whakaiti i to tuumaui mate. Kei roto i enei:
- Kaore i te momi hikareti. Mena he kaipaipa koe, kati te kai momi. Mena kaore koe e paowa, kaua e tiimata. Ko te momi hikareti te tino take morearea mo te mate pukupuku whakatuma e ora ai te hunga mate AAT.
- Whai i te kai pai
- Te whakakori tinana i ia wa
- Te kitenga i to kaiwhakarato hauora i nga wa katoa
- Te tango i nga rongoa e rite ana ki ta te kaiwhakarato
Mena he paatai taau mo o hua, korero ki to kaiwhakarato hauora.
Ako atu mo nga whakamatautau taiwhanga, awhe tohutoro, me te maarama ki nga hua.
He mea ano me mohio au mo te whakamatautau AAT?
I mua i te whakaae kia whakamatautauria, ka pai pea te korero me te kaitohutohu a-ira. Ko te kaitohutohu a-ira he tohunga ngaio whakangungu i roto i te whakapapa me te whakamatau ira. Ka taea e te kaitohutohu te awhina i a koe ki te maarama ki nga morearea me nga painga o te whakamatautau. Mena ka whakamatautauria koe, ka taea e te kaitohutohu te awhina i a koe ki te maarama ki nga hua me te tuku korero mo te ahuatanga, tae atu ki to tuponotanga ki te tuku i te mate ki o tamariki.
Tohutoro
- Nga Whakamatautau Reipa Aipurangi [Ipurangi]. Washington D.C .: American Association mo te Haumanu Haumanu; c2001–2019. Arepa-1 Antitrypsin; [whakahoutia 2019 Jun 7; whakahuahia 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai i: https://labtestsonline.org/tests/alpha-1-antitrypsin
- Nga Whakamatautau Reipa Aipurangi [Ipurangi]. Washington D.C .: American Association mo te Haumanu Haumanu; c2001–2019. Jaundice; [whakahoutia 2018 Pepuere 2; whakahuahia 2019 Oketopa 1]; [tata ki te 3 nga mata]. Wātea mai i: https://labtestsonline.org/conditions/jaundice
- Merck Manual Kaihoko Putanga [Ipurangi]. Kenilworth (NJ): Merck & Co. Inc.; c2019. Alpha-1 Antitrypsin Ngoikoretanga; [whakahoutia 2018 Nov; whakahuahia 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai:
- National Heart, Lung, and Blood Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. Alpha-1 Antitrypsin Ngoikoretanga; [whakahua 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai i: https://www.nhlbi.nih.gov/health-topics/alpha-1-antitrypsin-deficiency
- National Heart, Lung, and Blood Institute [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. Nga Whakamatau Toto; [whakahua 2019 Oketopa 1]; [tata ki te 3 nga mata]. Wātea mai i: https://www.nhlbi.nih.gov/health-topics/blood-tests
- NIH U.S. National Library of Medicine: Genetics Home Tohunga [Ipurangi]. Bethesda (MD): Te Tari Hauora me nga Ratonga Tangata a U.S. He aha te ira? 2019 Oketopa 1 [whakahua 2019 Oketopa 1]; [tata ki te 3 nga mata]. Wātea mai i: https://ghr.nlm.nih.gov/primer/basics/gene
- Hauora UF: Te Whare Waananga o Florida Hauora [Ipurangi]. Gainesville (FL): Te Whare Waananga o Florida Hauora; c2019. Ira-1 whakamātautau toto antitrypsin: Tirohanga; [whakahoutia 2019 Oketopa 1; whakahuahia 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai i: https://ufhealth.org/alpha-1-antitrypsin-blood-test
- Whare Wananga o Rochester Medical Center [Ipurangi]. Rochester (NY): Whare Wananga o Rochester Medical Center; c2019. Encyclopedia Hauora: Alpha-1 Antitrypsin; [whakahua 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai i: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_1_antitrypsin
- Hauora UW [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2019. Tohu Ira-1 Antitrypsin Whakamatau Tohu: He aha te Ira-1 Antitrypsin Ngoikoretanga ?; [whakahoutia 2018 Sep 5; whakahuahia 2019 Oketopa 1]; [tata ki te 2 nga mata]. Wātea mai:
- Hauora UW [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2019. Whakamatau Ira-1 Antitrypsin Whakamatau Tohu: He aha te Tohutohu Taketake ?; [whakahoutia 2018 Sep 5; whakahuahia 2019 Oketopa 1]; [tata ki te 7 o nga mata]. Wātea mai i: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#tv8548
- Hauora UW [Ipurangi]. Madison (WI): Te Whare Waananga o Wisconsin Whare Hauora me te Mana Haumanu; c2019. Whakamatau Ira-1 Antitrypsin Whakamatau Tohu: He aha E kore ahau e Whakamatauria ?; [whakahoutia 2018 Sep 5; whakahuahia 2019 Oketopa 1]; [tata ki te 6 o nga mata]. Wātea mai i: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#uf6790
Ko nga korero kei tenei papaanga kaua e whakamahia hei whakakapi mo te tiaki ngaio ngaio, tohutohu ranei. Whakapa atu ki te kaiwhakarato hauora mena he paatai taau mo to hauora.